The ancient traditional knowledge of medicinal properties of mushrooms comes from the Far East and particularly from China, Japan, Korea and northern Russia and eastern Europe. The mushrooms were and still are very important for American Indians. The Emperors of the great royal dynasty Chinese drank tea and mushroom concoctions to increase the vitality and longevity. The medicinal properties of Ganoderma lucidum were mentioned for the first time during the reign of the first Chinese emperor Shin Huang Ch'in Dynasty. In ancient China, Reishi or Ling zhi, adored for her ability to give health, wealth and eternal youth, was considered to as a god, with nearly 700 years ago was painted on the walls of a Chinese temple, the "Divinity Reishi" ("Reishi Goddess" or "Reishi Senshi").
The pharmacopoeia Pen T'sao Kang Mu describes the use of Ling zhi in this way: "... support a positive life energy and the IQ of the heart ...." In it is written that also increases intellectual capacity and improves memory. The Shiitake or Ku Shiang is traditionally known for its culinary value. The raw or dried Shiitake was used since ancient times for its taste and aroma. In many cultures of the Native Americans were used hallucinogenic mushrooms practices for medicinal, spiritual and healing for them, in fact, each disease was related to a spiritual malaise, and for this reason was also addressed at that level. These practices, which included the use of hallucinogenic mushrooms, they were very old, but were almost abolished with the advent of the Spaniards. Western civilizations have only recently started to explore the vast potential of medicinal mushrooms, but interest is increasing and the number of scientific studies in this regard is increasing rapidly. Between the end of the 20th century and the beginning of the 21st, the production of mushrooms has grown exponentially both in the development of new and modern technologies (sterile cultivation, cultured mycelium ...) and for the growth of popular awareness of the nutritional properties of mushrooms and healthy. World production of Shiitake (Lentinus edodes), for example, grew from 200,000 tons in 1986 to 3 million tonnes in 2006.
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